• Card 4 / 34: A 62 year-old woman complains of progressive dysphagia to both solids and liquids. She has intermittent symptoms of heartburn. Her physical exam is remarkable for very taut skin on the face as well as sclerodactly. An upper endoscopy is unrevealing. An esophageal motility study is performed. Which of the following manometric findings is most likely in this patient?
    1.) High LES pressure; Low or absent peristaltic activity in the esophageal body; Normal LES relaxation with swallowing
    2.) High LES pressure; Normal peristaltic activity in the esophageal body; Abnormal LES relaxation with swallowing
    3.) Low LES pressure; Low or absent peristaltic activity in the esophageal body with swallowing; Abnormal LES relaxation with swallowing
    4.) Low LES pressure; Normal peristaltic activity in the esophageal body; Normal LES relaxation with swallowing
    5.) Low LES pressure; Normal peristaltic activity in the esophageal body; Abnormal LES relaxation with swallowing

    Answer:
    3.) Low LES pressure; Low or absent peristaltic activity in the esophageal body with swallowing; Abnormal LES relaxation with swallowing

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Explanation:

Esophageal motility findings in scleroderma due to infiltration of esophagus with fibrosis.

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Gastrointestinal Pathophysiology Self-Assessment

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Access: Public

Attribution:  Laurence Scott Bailen, Tamsin Knox, Paul Abourjaily, Fredric D. Gordon,Marshall Kaplan,Andrew G. Plaut. PPY 222 Gastrointestinal Pathophysiology, Spring 2007. (Tufts University OpenCourseWare), http://ocw.tufts.edu/Course/47 (Accessed 3 May, 2014). License: Creative Commons BY-NC-SA
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